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The HC is responsiblefor receptor-mediated binding and membrane translocation. It begins with thephosphorylation of tyrosine kinases Janus kinase 1 (JAK-1) and JAK-3, which is followed bythe phosphorylation of tyrosine residues on the IL-2R ?-chain

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Glutathione S-transferaseM1 (GSTM1) and glutathione S-transferase T1 (GSTT1) null polymorphisms,smoking, and their interaction in oral cancer: a HuGE review and meta-analysis.
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