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Furthermore, in ALI/ARDS thereis a signi?cant portion of the intrathoracic gasvolume occupied by tissue oedema, ?uids andin?ammatory cells, as evidenced by computedtomographic studies; therefore lung gas volumemeasurements may not always be predictive oftotal thoracic volume (Gattinoni et al. Themean duration of mechanical ventilation was 4.8days [3–7 days] (Kurachek et al

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